EVALUATION OF THE PERFORMANCE OF MAGNETIC RESONANCE IMAGING IN THE EXPLORATION OF THE LOCOREGIONAL EXTENSION OF ENDOMETRIALCANCER: ABOUT 42 CASES

Introduction and purpose of the study : Endometrial cancer is the third most common gynaecological cancer in Morocco its therapeutic management depends on a precise staging of radiological (myometrial invasion, cervical and ganglionic involvement) and histological (histological type and degree of differentiation)initial workup. This pre-treatment evaluation may over or under treat patients, hence the aim of this work which will evaluate the contribution of magnetic resonance imaging in assessing myometrial invasion and lymph node involvement.

Materials and Methods: This is a single-centre retrospective study of a series of patients operated for endometrial cancer who underwent preoperative pelvic MRI in our Institute between January 1, 2014 and January 1, 2018. MRI data were collected from initial reports and compared with postoperative histological data.

Results and statistical analysis: 42 patients were included. Deep myometrial infiltration was found in 21 patients on MRI versus 25 patients on histology, with a sensitivity of 64% and specificity of 70.58% a positive predictive value of 76.19% and a negative predictive value of 57.14%. Pelvic and/or lomboaortic adenopathies were found in 11 patients on MRI compared to 6 patients on Histology with a sensitivity of 66.66% and specificity of 81.57%, a positive predictive value of 36.36% and a negative predictive value of 93.93%.

Conclusion: According to our study, MRI is not sufficiently accurate to detect the percentage of myometrial invasion and to identify the lymph node status.