Published June 22, 2023
| Version 1.1.0
Dataset
Open
Supporting data for "Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche"
Authors/Creators
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Fetahu, Irfete S.1
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Esser-Skala, Wolfgang2
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Dnyansagar, Rohit2
- Sindelar, Samuel2
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Rifatbegovic, Fikret1
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Bileck, Andrea3
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Skos, Lukas4
- Bozsaky, Eva1
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Lazic, Daria1
- Shaw, Lisa5
- Tötzl, Marcus1
- Tarlungeanu, Dora1
- Bernkopf, Marie1
- Rados, Magdalena1
- Weninger, Wolfgang5
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Tomazou, Eleni M.1
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Bock, Christoph6
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Gerner, Christopher3
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Ladenstein, Ruth1
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Farlik, Matthias5
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Fortelny, Nikolaus2
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Taschner-Mandl, Sabine1
- 1. St. Anna Children's Cancer Research Institute, Vienna, Austria
- 2. Department of Biosciences and Medical Biology, University of Salzburg, Salzburg, Austria
- 3. Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria; and Joint Metabolomics Facility, University and Medical University of Vienna, Vienna, Austria
- 4. Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Vienna, Austria
- 5. Department of Dermatology, Medical University of Vienna, Vienna, Austria
- 6. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria; and Center for Medical Statistics, Informatics and Intelligent Systems, Institute of Artificial Intelligence, Medical University of Vienna, Vienna, Austria
Description
This data repository contains several datasets supplementing the paper “Dissecting the cellular architecture of neuroblastoma bone marrow metastasis using single-cell transcriptomics and epigenomics unravels the role of monocytes at the metastatic niche” by Fetahu, Esser-Skala, Dnyansagar et al. (2023).
- HOMER_Results.zip: detailed results of the HOMER analysis
- nblast_scopen_gene_activity_normalized_motifs_added.rds: Seurat object with scATAC-seq data
- snp_array.tgz: SNP array data
- R_data_generated.tgz: Files generated by the scRNA-seq analysis scripts in the GitHub repository associated with the publication.
Notes
This study was funded by the Vienna Science and Technology Fund (WWTF#LS18-111, to S.T.M., N.F., and R.L.), MAPMET (FWF#P35841-B, to S.T.M.) by the Austrian Science Fund and LIQUIDHOPE (FWF#I4162, to S.T.M.) by the Transcan-2/ERA-NET initiative, EPICODE (FWF#P35072 to I.S.F.) by the Austrian Science Fund grant, and the St. Anna Kinderkrebsforschung e.V.
Files
HOMER_Results.zip
Additional details
Related works
- Is required by
- Software: https://github.com/csbg/neuroblastoma (URL)