ROYAL JELLY AND BEE HONEY COMBINATION – A NEW PERSPECTIVE FOR ANTIBACTERIAL THERAPY OF SKIN AND INTESTINAL INFECTIONS
Authors/Creators
- 1. Trakia University, Faculty of Veterinary Medicine, Stara Zagora, Bulgaria
Description
The article discusses data on the specific antibacterial activity of royal jelly and rape honey mixtures against antibiotic-resistant microorganisms. The combination of royal jelly and rape honey in a ratio of 1:100 (w/w) in concentrations of 10% and 30% (v/v) changed the sensitivity of a pathogenic E. coli strain – being previously resistant, it has acquired sensitivity after incubation with various antibacterial agents: gentamicin, amoxicillin, chloramphenicol, doxycycline and trimethoprim – sulfamethoxazole. These data could be useful in the future development of effective medicines.
Files
vol-7-2_2022-22-29.pdf
Additional details
Related works
- Is documented by
- Journal article: https://scij-tmvm.com/vol./vol.7/2/vol-7-2_2022-22-29.pdf (URL)
References
- Antimicrobial resistance: Global Report on Surveillance. W. H. Organization. (2014). http://apps.who.int/iris/ bitstream/10665/112642/1/9789241564748_eng.pdf.
- Blum M. S., Novak A. F., Taber S. (1959). 10-Hydroxy-Δ2-decenoic acid, an antibiotic found in royal jelly. Science, 130, 452–453
- Bogdanov S. (1997). Nature and origin of the antibacterial substances in honey. Lebensmittelwis-senschaft und Technologie, 30, 748–753.
- Bogdanov S., Martin P., Lüllman C. (1997). Harmonized methods of the European Honey Commission. Apidologie, Extra Issue 1-59, Elsevier/INRA/DIB/AGIB.
- Castro S. B. R., Leal C. A. G.., Freire F. R.., Carvalho D. A., Oliveira D. F., Figueiredo H. C. P.. (2008). Antibacterial activity of plant extracts from Brazil against fish pathogenic bacteria. Brazilian Journal of Mi-crobiology, 39, 756–760.
- CLSI. (2008). Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals.Approved Standard – Third Edition, CLSI document M31–A3, Vol. 28, No. 8, ISBN 1-56238-659-X, Wayne, PA
- Dinkov D. (2016). The antibacterial activity of acacia, multifloral and oak honeydew honeys. Inter-national Journal of Veterinary Sciences and Animal Husbandry, Vol.1, Issue 2, Part A:07–10.
- Dinkov D., Stratev D., Balkanska R., Sergelidis D., Vashin Iv. (2016). Reduction effect of Royal jelly and Rape honey alone and in combination against Methicillin-resistant Staphylococcus aureus (MRSA) strains. Journal of Bacteriology and Virology, Vol. 46, 1, 1–8.
- Dinkov, D. (2017). Perspection of Royal Jelly and Bee Honey as new antibacterial therapy agents of hospital infections. Journal of Clinical Pathology & Laboratory Medicine, Review article, Vol.1, 1: 5–8 – http://www.alliedacademies.org/clinical-pathology-laboratory-medicine/
- Dinkov D., Stratev D., Balkanska R. (2014). In vitro antibacterial activity of Royal Gelly against pathogen Escherichia coli. Veterinary Journal of Republic of Srpska, Vol.XIV, 1, 14–25, Banja Luka, DOI 10.7251 – EBSCO, Worldcat.
- Gethin G., Cowman S. (2008). Bacteriological changes in sloughy venous leg ulcers treated with manuka honey or hydrogel: an RCT. Journal of Wound Care, 17, 241-244, 246-247.
- Leung R., Ho A., Chan J., Choy D., Lai C. K. (1997). Royal jelly consumption and hypersensitivity in the community. Clinical and Experimental Allergy, 27(3), 333–336.
- Li J., Wang T., Peng W.J. (2007). Comparative analysis of the effects of different storage conditions on major royal jelly proteins. Journal of Apicultural Research. 46(2), 73–80.
- Li J. K., Feng M., Begna D., Fang Y., Zheng A. J. (2010). Proteome Comparison of Hypopharyngeal Gland Development between Italian and Royal Jelly-Producing Worker Honeybees (Apis mellifera L). Journal of Proteome Research, 9 (12), 6578–6594.
- Lombardi C., Senna G. E., Gatti B., Feligioni M., Riva G., Bonadonna P., Dama A. R., Canonica G. W., Passalacqua G. (1998). Allergic reactions to honey and royal jelly and their relationship with sensitization to compositae. Allergologia Et Immunopathologia (Madr), 26(6), 288–290.
- Mavric E., Wittmann S., Barth G., Henle T. (2008). Identification and quantification of methylgly-oxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand. Molecular Nutrition & Food Research, 52, 483–489.
- Melliou E., Chinou I. (2005). Chemistry and bioactivity of royal jelly from Greece, Journal of Agri-cultural and Food Chemistry. 53, 8987–8992.
- ОN 2576693-84. (1984). Fresh and lyophilized royal jelly (in Bulgarian).
- Palumbo S. A., Morgan D. R., Buchanan R. T. (1985). Influence of Temperature, NaCI, and pH on the Growth of Aeromonas Hydrophila. Journal of Food Science, 50, 1417–1421.
- Patton T., Barrett J., Brennan J., Moran N. (2006). Use of a spectrophotometric bioassay for deter-mination of microbial sensitivity to manuka honey. Journal of Microbiology Methods, 64, 84–95.
- Sesta G. (2006). Determination of sugars in royal jelly by HPLC. Apidologie, 37, 84–90.
- Shen L. R., Ding M. H., Zhang L. W., Jin F., Zhang W.G., Li D. (2010). Expression of Acc-Royalisin Gene from Royal Jelly of Chinese Honeybee in Escherichia coli and Its Antibacterial Activity. Jour-nal of Agricultural and Food Chemistry, 58 (4), 2266–2273.
- Sherlock O., Dolan A., Athman R., Power A., Gethin G., Gowman S., Humphreys H., (2010). Com-parison of the antimicrobial activity of Ulmo honey from Chile and Manuka honey against methicil-lin-resistant Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. BMC Comple-mentary and Alternative Medicine, 10, 47
- Shirzad H., Shahinfard N., Naficy M. R., Karami M. (2007). Comparison of royal jelly effects with gentamicin and ceftriaxone on the growth of Escherichia coli, Bacillus cereus, Pseudomonas aeru-ginosa, Staphylococcus aureus, in a laboratory environment. Tropical Medicine & International Health, 12, 159.
- Stratev D., Vashin Iv., Balkanska R., Dinkov D. (2015). Antibacterial activity of Royal jelly and rape honey against Aeromonas hydrophila (ATCC 7965). Journal of Food and Healh Science, 1(2), 64–74.
- Takahama H., Shimazu T. (2006). Food-induced anaphylaxis caused by ingestion of royal jelly. Journal of Dermatology, 33(6), 424–426.
- Taormina P. J., Niemira B. A., Beuchat L. R. (2001). Inhibitory activity of honey against foodborne pathogens as influenced by the presence of hydrogen peroxide and level of antioxidant power. In-ternational Journal of Food Microbiology, 69, 217–225.
- Tortorello M. (2003). Indicator Orgnanisms for Safety and Quality – Uses and Methods for Detec-tion. Minireview. Journal of AOAC International, 86, 1208–1217
- Von der Ohe W., Piana M.L., Morlot M., Martin P. (2004). Harmonized methods of melissopalynol-ogy. Apidologie, 35, 18–25.
- Wilkinson J. M., Cavanagh H. M. A. (2005). Antibacterial Activity of 13 Honeys Against Esche-richia coli and Pseudomonas aeruginosa. Journal of Medicinal Food, 8 (1), 100–103.
- Willix D.J., Molan P.C., Harfoot C.G. (1992). A comparison of the sensitivity of wound-infecting species of bacteria to the antibacterial activity of manuka honey and other honey. Journal of applied bacteriology, 73, 388–394