Published February 20, 2023 | Version v1.1
Software Open

Antibody library design with Transformer and Deep Reinforcement Learning -- source code and data

Creators

  • 1. KAUST
  • 2. Chinese Academy of Sciences

Description

This is the source code for AB-Gen, a tool for antibody library design. It can efficiently explore the antibody space and design CDRH3 sequences that fulfill multi-property constraints.

  • Publication: TBA
  • Files included in this release:
    • 1.pipeline.jpg: the workflow of AB-Gen.
    • charlesxu90/ab-gen-v1.0.zip: the source code of AB-Gen.
    • data.zip: the filtered datasets to train the prior model, the pretrained models, and the designed sequences. 

Files

1.pipeline.jpg

Files (710.7 MB)

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Additional details

Related works

Is supplement to
https://github.com/charlesxu90/ab-gen/tree/v1.0 (URL)