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Screening for nucleoside inhibitors of the SARS-CoV-2 RdRP

Van Damme, Ellen

This report describes the most relevant results of screening compounds with a nucleoside analogue structure from the Janssen Pharmaceutica compound collection for potential activity against SARS-CoV-2 in a cell-based assay and nucleoside triphosphates in a radioactive filtering binding RdRP assay.

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