Estimating national-level measles case–fatality ratios in low-income and middle-income countries: an updated systematic review and modelling study

To understand current and prevent future measles mortality burden, it is critical to have robust estimates of measles case fatality. Dynamic estimates of measles case fatality ratios (CFR) that are age-, location-, and time-specific are essential to capture variation in underlying population-level factors that contribute systematically to increases or decreases in case fatality, such as vaccination coverage and measles incidence. In this study, we updated estimates of measles CFR by expanding upon previous systematic reviews and implementing a meta-regression model.