Published November 16, 2021 | Version v1
Dataset Open

Long-read transcriptome data (Iso-Seq) of the human and mouse brain

  • 1. University of Exeter

Description

Datasets from "Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing", SK.Leung, A.Jeffries. et al. (2021)

Deposited files are generated from running Cupcake, SQANTI2 (v7.4) and filter. 
Note, only the files generated from SQANTI2 filtering are deposited. 
To re-run SQANTI, use the files in cupcake_collapse folder as input. 

Please refer to code (https://github.com/SziKayLeung/Whole_Transcriptome_Paper) for more information. 

Datasets: 
- AdultCTX: Adult human prefrontal cortex tissue (n = 4) merged dataset
- FetalCTX: Fetal human prefrontal cortex tissue (n = 3) merged dataset
- FetalHIP: Fetal human hippocampus tissue (n = 2, subset of FetalCTX) merged dataset
- FetalSTR: Fetal human striatum tissue (n = 2, subset of FetalCTX) merged dataset
- MouseCTX: Mouse entorhinal cortex tissue (n = 12) merged dataset

Files

Cupcake_collapse.zip

Files (488.0 MB)

Name Size Download all
md5:e0c6757b912ef8735d5dbeddae22f5e0
262.0 MB Preview Download
md5:caad23cc57b4444316e13d04c8b9abf6
226.1 MB Preview Download

Additional details

Related works

Is supplemented by
Journal article: 10.1016/j.celrep.2021.110022 (DOI)
Software: 10.5281/zenodo.5588498 (DOI)