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Published November 15, 2021 | Version Version 1
Dataset Open

Electrophysiological characterization and functionality of neurons in murine cerebral organoids.

Authors/Creators

  • 1. University of Modena and Reggio Emilia
  • 2. University of Verona

Contributors

Work package leader:

  • 1. University of Modena and Reggio Emilia
  • 2. University of Verona

Description

Dataset includes patch-clamp recordings aim to characterize functionality of neurons belonging to murine cerebral organoids.

Patch-clamp recordings were performed by University of Modena and Reggio Emilia unit (PI Prof. Curia Giulia).

Organoids were generated by University of Verona unit (PI Prof. Decimo Ilaria) and transferred to Modena for electrophysiology experiments.

Files

HERMES_Patch_Organoids_General Info.zip

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Additional details

Related works

Is published in
Journal article: 10.1016/j.isci.2021.103438 (DOI)

Funding

European Commission
HERMES - Hybrid Enhanced Regenerative Medicine Systems 824164

References

  • Ciarpella F, Zamfir RG, Campanelli A, Ren E, Pedrotti G, Bottani E, Borioli A, Caron D, Di Chio M, Dolci S, Ahtiainen A, Malpeli G, Malerba G, Bardoni R, Fumagalli G, Hyttinen J, Bifari F, Palazzolo G, Panuccio G, Curia G, Decimo I. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. iScience. 2021; 24(12):103438. doi: 10.1016/j.isci.2021.103438.