Comparison of the safety and efficacy of nalbuphine 10 mg with 0.125% bupivacaine versusbutorphanol 2 mg with 0.125% bupivacaine by epidural route for providing postoperative analgesia in patients undergoing elective abdominal surgeries

Comparison of the safety and efficacy of nalbuphine 10 mg with 0.125% bupivacaine versusbutorphanol 2 mg with 0.125% bupivacaine by epidural route for providing postoperative analgesia in patients undergoing elective abdominal surgeries. Methodology: The patients were randomly allocated into two groupsGROUP BB: received 2 ml of butorphanolwith 2.5 ml of 0.5% bupivacaine, diluted in normal saline to 10 ml. Butorphanol 2 mg + 0.125% bupivacaine GROUP BN (control group): received 1 ml of nalbuphine with 2.5 ml of 0.5% bupivacaine, diluted in normal saline to 10 ml. Nalbuphine 10 mg + 0.125% bupivacaine. In the postoperative period, when the patients complained of pain, the intensity of pain was assessed using the VAS scaleThe pain intensity was assessed by VAS score at 0, 15, 30, 60 minutes, 2, 4, 6, 8, and 10 hours after epidural injection ,onset of analgesia, duration of analgesia, Systolic blood pressure, diastolic blood pressure, pulse rate, and respiratory rate were recorded at 0, 15, 30, 60 minutes, 2, 4, 6, 8, and 10 hours after epidural injection. SpO2 monitored continuously. Results: The mean time of onset of analgesia in group BN was 8.57±1.25 minutes, and the meantime of onset of analgesia in group BB was 6.90±0.99 minutes.The mean duration of analgesia was 5.06±0.75 hours in group BN, and the mean duration of analgesia was 7.07±1.66 hours in group BB. Conclusion: Butorphanol 2 mg with 0.125% bupivacaine provided faster onset of analgesia and longer duration of analgesia than with nalbuphine 10 mg with 0.125% bupivacaine