Published January 21, 2023 | Version v1

INSPIRE-seq simultaneously selects nanobodies for immune epitopes in the complex tumor microenvironment

  • 1. Department of Radiation Oncology, Department of Microbiology, Pondicherry University, Kalapet, Puducherry, India the University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • 2. Department of Radiation Oncology, the University of Texas Southwestern Medical Center, Dallas, TX, USA
  • 3. Department of Chemistry and Cent Institute for Drug Discovery, Leipzig University Medical School, Leipzig, Germany.er for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA.
  • 4. Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA
  • 5. Department of Pharmacology, University of California San Diego, La Jolla, CA, USA

Description

scRNAseq of CD45 magnetic microbeads enriched cells were isolated form Py8119 bearing mice (three mice per pool/group) two hours after injection of either PBS, insertless phage display, CD45, DCs, or CD8 specific VHHs phage display libraries. 

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