Published January 27, 2022 | Version 1
Dataset Restricted

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

  • 1. Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy
  • 2. Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy and Department of Surgery, Dentistry, Pediatrics and Gynecology, Cardiovascular Science, The University of Verona, Verona, Italy
  • 3. Coronary Care Unit and Laboratory of Experimental Cardiology, Department of Cardiothoracic and Vascular Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
  • 4. First Department of Medicine, Cardiology, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany and DZHK (German Centre for Cardiovascular Research)—Partner Site Munich Heart Alliance, Munich, Germany
  • 5. Istituto Auxologico Italiano IRCCS, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy and Istituto Auxologico Italiano, IRCCS, Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy and Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy
  • 6. Coronary Care Unit and Laboratory of Experimental Cardiology, Department of Cardiothoracic and Vascular Sciences, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy and Unit of Cardiology, Department of Molecular Medicine, University of Pavia, Pavia, Italy

Description

Raw and unfiltered datasets used for the publication.

Notes

This work was supported by the Marie Skłodowska-Curie Individual Fellowship (H2020-MSCA-IF-2017 No. 795209) to LS, the Fondazione CARIPLO, "Biomedical Research Conducted by Young Researchers" (Grant No. 2019-1691) to LS, the Leducq Foundation for Cardiovascular Research [18CVD05] "Toward Precision Medicine with Human iPSCs for Cardiac Channelopathies" to PS, MG, LC, LS, MM, the Ph.D. fellowship from the University of Verona to VL, the DZHK and the German Research Foundation Transregio Research Units 152 and 267 to AM.

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Additional details

Related works

Is source of
Journal article: 10.3389/fphys.2021.730127 (DOI)

Funding

European Commission
PREMEDiCARE - PREcision MEDicine with induced pluripotent stem cells for Cardiac Arrhythmias Risk Evaluation 795209