PHYTOCHEMICAL SCREENING AND IN VITRO ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OF CINNAMOMUM VERUM (BARK)

Traditional  herbal  medicines  are  naturally  occurring,  plant-derived  substances  with  minimal  or  no  requirement  of  industrial  processing  that  has  been  used  to  treat illness within local or regional healing practices. The utilization and application of plants for healing purposes predate human history and lead to the origin of much modern  medicine.  Traditional  herbal  medicines  are  naturally  occurring,  plant-derived  substances  with  minimal  or  no  requirement  of  industrial  processing  that  has  been  used  to  treat illness within local or regional healing practices. The utilization and application of plants for healing purposes predate human history and lead to the origin of much modern  medicine.  The ethnomedicinal data reveals plant is a potential source for the treatment of bronchitis, cardiac disorder, cephalalgia, cardiac diseases, diarrhea, uropathy, fever, arthritis, coughing, impotence, frigidity, intestinal spasms, vaginitis, neuralgia, rheumatism. This study deals with Phytochemical screening and in vitro anti -inflammatory activity of aqueous extract of Cinnamomum verum bark. The plant material was collected and subjected to extraction by distilled water. Further phytochemical test and anti -inflammatory activity of the extract was evaluated. The results showed that The percentage yield of aqueous extract of Cinnamomum verum was found to be 16.12% with dark brown colour. The phytoconstituents like Alkaloids, Saponins, Phenols, Carbohydrates, Flavonoids, Proteins & amino acids, Diterpenes were found to be present. The percentage inhibition for standard drug diclofenac was found to be 313.70% while for aqueous extract of Cinnamomum verum the IC50 value was found to be 268.29%. The results indicate that the aqueous extract of Cinnamomum verum have more potent anti -inflammatory effect than standard drug diclofenac.

Keywords: Cinnamomum verum, Anti -inflammatory activity, Phytochemicals, Herbal medicines.