Prospective Analysis of Perfusion CT Imaging of Liver Pathology and Histopathological Relation
Authors/Creators
- 1. Assistant Professor, Department of Radiology, Banas Medical College and Research Institute Palanpur, Gujarat
- 2. Professor, Department of Physiology, Banas Medical College and Research Institute Palanpur, Gujarat
Description
Background and Aim: The existence and size of tumor vasculature are closely correlated with CT perfusion parameters, which may be used for earlier liver cancer detection and more individualized patient monitoring. The purpose of the current study was to contrast the histological diagnosis with the imaging diagnostic of liver lesions utilising CT perfusion parameters.
Material and Methods: 100 patients who had liver space-occupying lesions by conventional and contrast-enhanced US, CT, or MRI made up the study's population. Prior to participating in the study, all patients were required to give written informed consent. The 16 SLICE CT scanner and syngo® Body Perfusion CT software were used for all CT perfusion tests. The method is based on a continuous accusation of dynamic contrast flow in cine mode.
Results: When perfusion parameters were compared between a few common benign lesions, including liver abscess and hydatid cyst, and normal liver parenchyma, it was discovered that there was a reduction in intralesional BV, BF, PERM, ALP, PVP, and HPI among these benign liver lesions, indicating the cystic content of the lesion. In contrast, there was a relatively higher intralesional BF, ALP, and HP
Conclusion: Using the perfusion parameters, CT perfusion imaging of the liver can be used to distinguish between focal lesions of the liver and functional information about the microcirculation of normal parenchyma. It is an effective method for identifying primary or metastatic tumors.