Lipurometriocnemus Saether (Diptera: Chironomidae: Orthocladiinae) is composed of five species endemic to the American continent. Three new species from Argentina are described and illustrated as males and Austrocladius barilochensis (Edwards) is newly transferred to Lipurometriocnemus. A cladistic analysis of Orthocladiinae placed Lipurometriocnemus as sister group to Metriocnemus van der Wulp. A separate cladistic analysis of Lipurometriocnemus species was also conducted and the results are discussed. An identification key to the adult males of Lipurometriocnemus is provided.