Published December 22, 2022
| Version v1
Dataset
Open
Multiplexed histology of COVID-19 post-mortem lung samples - Single-cell Mean Fluorescence Intensities
Authors/Creators
- 1. Deutsches Rheuma-Forschungszentrum & Charité-Universitätsmedizin Berlin
- 2. Charité-Universitätsmedizin Berlin
Description
Data table containing single-cell mean fluorescence intensities (MFI) of all markers analyzed by multiplexed histology in all COVID-19 post-mortem lung samples and non-COVID-related pneumonia controls (14 lung samples, stratified based on disease duration into control, acute, chronic and prolonged). It contains information at the single-cell level about approx 50 proteins in around 40.000 lung cells.
Data shown has been arcsin(h) transformed with a co-factor of 0.2. Additionally, cells expressing less than 0.15 MFI of all markers have been labeled as non-defined and excluded from the data set.
Notes
Funding: Deutsche Forschungsgemeinschaft HA5354/10-1, SPP1937 (HA5354/8-2) and TRR130 P17 and C01 (to Anja Hauser)
Files
Files
(20.0 MB)
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md5:a1799f4ac8108ff7c3b1364596f6b89b
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20.0 MB | Download |
Additional details
References
- Mothes, R. and Pascual-Reguant, A. et al. Local CCL18 and CCL21 expand lung fibrovascular niches and recruit lymphocytes, leading to tertiary lymphoid structure formation in prolonged COVID-19. medRxiv 2022.03.24.22272768 (2022) doi:10.1101/2022.03.24.22272768.