Published December 22, 2022 | Version v1

Data for "Coordination of bacterial cell wall and outer membrane biosynthesis"

  • 1. Department of Microbiology, Harvard Medical School
  • 2. Department of Systems Biology, Harvard Medical School

Description

Raw data used in the paper "Coordination of bacterial cell wall and outer membrane biosynthesis" by Katherine R. Hummels, Samuel P. Berry, Zhaoqi Li, Atsushi Taguchi, Joseph K. Min, Suzanne Walker, Debora S. Marks, and Thomas G. Bernhardt. These data were collected with the aim of understanding how the lipopolysaccharide biosynthetic enzyme LpxC is regulated in diverse gram-negative bacteria, particularly Pseudomonas aeruginosa. The dataset contains the following tarred directories:

Experimental data

  • Microscopy (microscopy.tar.gz)
  • LC-MS/MS (lc-ms_ms.tar.gz)

Covariation analysis

  • Multiple sequence alignments (alignments.tar.gz)
  • AlphaFold structures (alphafold.tar.gz)
  • EVcomplex models and couplings (evcomplex.tar.gz)
  • Phylogenetic trees (trees.tar.gz)

For more detailed methods and file descriptions, please see README.md. Associated code for analysis can be found at https://github.com/samberry19/evcomplex-interaction-scoring.

Files

README.md

Files (6.8 GB)

Name Size
md5:28ab316d7e9588566921ccfc14bc68b2
56.2 MB Download
md5:4f4f58e1658ecf4613820828d14c26f6
2.5 GB Download
md5:addf51afaefc1ea15ebc7859d51346c5
1.6 GB Download
md5:4d00ce75531cee0e10e5617e61f43e5e
2.4 GB Download
md5:2b26159b8f30bb992f0f7ac945ce045b
111.5 MB Download
md5:0de092aa1f7222e1f306628276dbc3f6
6.9 kB Preview Download
md5:2b161627d1e0545dd0c0b87b53169881
15.2 MB Download