Published December 14, 2022 | Version v1

Zebrafish: Model for Organ Toxicity Studies

  • 1. Department of Veterinary Pharmacology and Toxicology, Nobel Polytechnic in Animal Husbandry College, Kamdhenu University, Junagadh, Gujarat, India 362310. Postal address: 40 Gaurav Park society, Thalota road, Visnagar- 384315.

Description

Animal research is important for drug development as it focuses; On understanding the biology & genetics of living organisms, to understand disease etiology & progression, to identify potential biochemical pathways (targets for drugs) to mitigate diseases and for the advance understanding of illnesses such as cancer, AIDS, chronic pain & many other medical conditions. Animal testing focuses on understanding four facets: Pharmacokinetics, pharmacodynamics, efficacy & safety or toxicity. Using animals in research is extremely beneficial as they are biologically similar to humans leading to a better result. Because laboratory animals have a short life cycle, they can be studied their entire lives which is crucial for a better understanding of how disease processes work.

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