Use of Polyene Macrolide Antibiotics In Combination With Dimethil Sulfoxide As Antiviral And Antifungal Agent At Plant Treatment

Comparative physical and chemical characteristics of dimethyl sulfoxide (DMSO) and polyene antibiotics (PA) have been presented in this paper. The effect of a complex interaction of DMSO and PA with bilayer lipid membranes was examined and the results of experimental studies of physical and chemical characteristics of amphotericin B and levorin molecules and the interaction with the membranes were discussed. On the basis of PA molecules a theoretical model of creating effective membrane-active preparation against viral and fungal diseases of plants was developed.