A SYSTEMATIC REVIEW ON FORMULATION AND DEVELOPMENT

The formulation development is important part of pharmaceutical development and essential for therapeutic and commercial success of product by providing quality, safety and efficiency. Formulation can determine patentability, lifecycle the success of a pharmaceutical product.  Pharmaceutical formulation development links the discovery of a new drug substance to the successful development of a commercial drug product. Formulation development is a stage of the pharmaceutical product development during which the physicochemical properties of the drug of drug substance are characterized and established the psychochemical and biopharmaceutical properties gives appropriate formulation and delivery methods. Apart from helping formulation development, Preformulation studies also help in lead identification during drug discovery phase.

Key words: Stability, dissolution, compatibility studies, Preformulation