Metagenome assembled genome database of a human cohort and fecal reactors
Description
HumanCohort_annotations.tsv.zip: This is the custom MAG database (n=2447 MAGs) and corresponding annotations that were used in Borton 2022: "Targeted curation of the gut microbial gene content modulating human cardiovascular disease". The citation will be updated upon publication of the manuscript. Metagenome assembled genomes were generated from fecal metagenomes derived from a 54 person cohort and anoxic methylated amine enrichments.
HumanCohortmetabolism_summary.xlsx.zip: This is the annotation summary for 2447 MAGs in the cohort database.
Quality_Abundance_CohortMAGs.xlsx: This is a genome inventory of the 2447 MAGs in the cohort database including genome statistics and relative abundance.
orig_1D_NMR_fids.zip: NMR data derived from anoxic methylated amine enrichments.
Files
HumanCohort_annotations.tsv.zip
Additional details
Funding
- National Institutes of Health
- Alternative routes of gut microbial methylamine metabolism that may limit trimethylamine N-oxide, a trigger for atherosclerosis. 1R01DK109345-01