Published November 27, 2022
| Version 1
Journal article
Open
Predicting In-depth mechanisms of action for cancer drugs
Description
Data for "Predicting In-depth mechanisms of action for cancer drugs." Please download these files and put them in a folder named "Data". Download the respective scripts from https://github.com/ruppinlab/drug.OnTarget
Notes
File Description:
onTarget (onTarget_v3.0.RDS): A single object is a curation of all the DepMap data including viability screens after CRISPR-Cas9 & drug treatment, expression & mutation of cell lines.
KnowTraget_prediction (KnownTarget_predictions_v4.RDS): Metadata of Drugs and their target+DeepTarget's top predicted target information
drugVScrispr_corr_features_list (drugVScrispr_corr_features_list.RDS): DKS Score & P for each gene vs each drug.
drugVScrispr_corr_features_list_secondary (drugVScrispr_corr_features_list_secondary.RDS): Secondary DKS Score & P for each gene vs each drug.
Files
BIOGRID-CHEMICALS-3.5.182.chemtab.txt
Files
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