Published May 9, 2023 | Version v1

[Data S1] Microbiota dictate T cell clonal selection to augment graft-vs-host disease after stem cell transplantation

Description

Data S1. ALICE hits for all recipient pairs amongst B6 to B6D2F1 transplants with or without antibiotic exposure and 900cGy vs. 1300cGy TBI conditioning. For each recipient pair (12 mice total, 66 pairs for spleen; 15 pairs for SILP analysis), all ALICE hits generated as described in methods.

Notes

This file contains ALICE output files referred to as Data S1. Antigen-specific lymphocyte identification by clustering of expanded sequences (ALICE) was performed as described in Pogorelyy et al (13), using publicly available code (https://github.com/pogorely/ALICE, last accessed 9/16/2021). Each analysis was run over 100 iterations consisting of 1x106 sequences/iteration for generative probability estimation simulation for each VJ class, as recommended in the original manuscript.

Files

TCR recips - 1906Tgut_G10_11 (ALICE).csv

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