Published November 23, 2022 | Version v1

Knowledge-driven design and optimization of potent symmetric anticancer molecules: A case study on PKM2 activators

  • 1. Birla Institute of Technology, Mesra
  • 2. University of Konstanz, Germany

Description

All the raw data files including 3D structures of all the 200 virtually designed palindromic and non-palindromic activators, 3D structures of top 5 palindromic and non-palindromic activators in complex with PKM2 protein, starting and ending conformations of MD simulation structures with the .tpr files for all six simulations for PDA116 and NPDA4 are available in this dataset.

Files

MD_structures.zip