Overview Of Transdermal Drug Delivery System

Transdermal drug delivery system (TDDS) has emerged as a potential novel drug delivery system within the last 30 years to boost the therapeutic efficacy and safety, maintain steady state plasma level of drugs and overcome important drawbacks of the traditional oral dosage forms and parenteral preparations. TDDS is ideally fitted to diseases that demand chronic treatment with frequent dosing. This review deals with a brief insight on the formulation aspects, the physical and chemical enhancers being explored to enhance the transdermal delivery of drugs across the stratum corneum, the evaluation parameters (physicochemical, in vitro, in vivo studies) and therapeutic applications of TDDS.