Nutrition Can Modify Gut-Brain Axis and Medication Induced Metabolic Disorders in Autism Spectrum Disorder- A Hypothesis
Authors/Creators
- 1. Food and Health group, Department of Land, Environment, Agriculture and Forestry, University of Padova, Padova, Italy
- 2. Department of physical education and sport sciences, Islamic Azad University, East Tehran Branch, Tehran, Iran
- 3. Department of physical education and sport sciences, University of Tehran, Tehran, Iran
Description
Autism Spectrum Disorder (ASD), is a neurodevelopmental disorder which is accompanied by several health-related challenges. Nutritional and gastrointestinal problems are common among individuals with ASD. Gut microbiota imbalance may be a reason of nutritional problems including food selectivity and restricted dietary intake. Nutritional problems and gut microbiota imbalance can increase behavioral symptoms which may increase the possibility and necessity for medication. It has been suggested that some medications, may increase the risk of metabolic impairments including glucose homeostasis abnormality, insulin resistance and/or diabetes. In this manuscript, we hypothesized that gut microbiota improvement via probiotic consumption, may improve GI problems and modify behavioral symptoms, which seems to manage medication prescription necessity.