Published September 13, 2022 | Version v1

Twist Whole-Exome Sequencing Dataset - High Coverage - WGGC SIG4 Benchmarking

Authors/Creators

  • 1. Core Unit for Bioinformatics Data Analysis, Medical Faculty, University of Bonn, Venusberg-Campus 1, 53127 Bonn, Germany

Contributors

Contact person:

Project manager:

  • 1. Institute of Genomic Statistics and Bioinformatics, University of Bonn, Bonn, Germany.
  • 2. Core Unit for Bioinformatics Data Analysis, Medical Faculty, University of Bonn, Venusberg-Campus 1, 53127 Bonn, Germany
  • 3. Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany

Description

GIAB Reference Genome for Benchmarking Initiatives in the West German Genome Center (WGGC) - SIG4. 

Twist Whole-Exome Sequencing Dataset - High Coverage - 200M Reads.

 

 

Files

md5sum.txt

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md5:c4a1cb11f8697cbfef5f5963da36a262
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md5:3c3c37eb8e140b3f9367d1565854f641
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md5:f14ff4ad78f13f3ab90935fa8b197dde
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Additional details

References

  • Krusche, P., Trigg, L., Boutros, P.C. et al. Best practices for benchmarking germline small-variant calls in human genomes. Nat Biotechnol 37, 555–560 (2019)
  • Zook, J., Catoe, D., McDaniel, J. et al. Extensive sequencing of seven human genomes to characterize benchmark reference materials. Sci Data 3, 160025 (2016)
  • Wagner, J., Olson, N.D., Harris, L. et al. Curated variation benchmarks for challenging medically relevant autosomal genes. Nat Biotechnol 40, 672–680 (2022)