Published August 18, 2022 | Version v1
Journal article Open

AN OVERVIEW OF DHEA-S LEVELS IN CHRONIC STRESS-PROSPECTIVE STUDY

  • 1. Associate professor, Department of Pathology, Padmashree Institute of Medical Laboratory Technology, Bengaluru-560060.
  • 2. Associate Professor, Department of Pathology, Padmashree Institute of Clinical Research, Bengaluru-560060.
  • 3. Professor, Department of Pathology, Padmashree Institute of Medical Laboratory Technology, Bengaluru-560060.

Description

Background: Increased stress levels are associated with various health issues due to the dysregulation of HPA axis, more so when the stress is chronic in nature.As the DHEA-S is a catabolic hormone the chronic stress levels may be involved with long term diseases like early ageing, hypertension, cancer and various other diseases 

Objectives: The aim of this study was to see the effect of perceived chronic stress in a subset of healthy population of male and female volunteers who willingly participated in the study. The selected male and female population was than stratified into age and stress matched groups and then one time DHEA-S levels were ascertained to see for changes in the DHEA-S values.

Methods: DHEA-S levels were measured within 6 hours of collection of the Blood Samples, randomly collected at different time points in the day by Chemiluminescence method which was than statistically evaluated by using Mini Tab statistical tool.

Results: There was no significant correlation in both genders when age and stress matched. 

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