Published September 1, 2022 | Version v1

Primary amyloidosis of vocal cord masquerading as malignancy- a rare presentation

  • 1. 1MD Pathology, Assistant Professor, Department of Pathology, Mahatma Gandhi University of medical sciences and technology, Jaipur 2MD Pathology, Assistant Professor,Department of Pathology, Mahatma Gandhi University of medical sciences and technology, Jaipur

Description

ABSTRACT-

Objective- To study role of histopathological examination for confirmation of Primary Amyloidosis of vocal cord and to differentiate the same from malignancy. Case report- Here, we present a case of isolated laryngeal amyloidosis in adult female which mimics malignancy clinically.  Amyloidosis is gradual in onset and has unpredictable manner. It is a benign, heterogeneous, multisystem organ disorder affecting many tissues and organs. More commonly it affects kidney, Spleen, Liver, Heart, tongue along with many endocrine organs. However, Primary involvement of larynx is a very rare phenomenon in clinical settings. Isolated amyloidosis of vocal cord is a rare entity in clinical practice with only 0.2 to 1.2% of benign tumors of larynx. Conclusion-Amyloidosis commonly mimics malignancy in clinical settings. Hence, it is mandatory to diagnose it accurately as it affects the treatment.

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