Numerical investigation of electroporation induced by a He and He-O2 (1000 ppm) plasma jets on healthy and cancerous skin tissues

Electroporation is used in electrochemotherapy, gene therapy, DNA transfer etc. Electroporation is typically achieved through conductive wires. In this abstract we describe an alternative and non-contact method of achieving electroporation, i.e. through the use of atmospheric pressure plasma jets (APPJs). In a recent study of Helium APPJ it was found that the addition of oxygen admixtures increased its effectiveness in cancer treatment. This effectiveness was attributed to reactive oxygen and nitrogen species (RONS) produced by the APPJ. However, a recent simulation study from our team showed that the oxygen admixtures increase the strength of the induced electric field (IEF) on the treated surface.