De novo assembly and annotation of parasitic trematode genomes

Contained in this release are 19 genome assemblies and annotations of parasitic trematodes, encompassing 13 species. This included representatives of the Schistosoma (n = 13 assemblies), Trichobilharzia (n = 2 assemblies), Heterobilharzia americana (n = 2 assemblies) and Dicrocoelium dendriticum (n = 1 assembly). The Schistosoma curassoni assembly has been released previously (10.5281/zenodo.6594833) but a new annotation is included with the original assembly here. 

These genomes were assembled from a variety of sources including stored parasites from museum collections, established laboratory strains and wild-caught isolates sampled from natural hosts in endemic regions. Using a combination of DNA sequencing approaches, all genomes were assembled into chromosomal-scale scaffolds. This was followed by genome annotation based on short-read RNA sequencing (RNA-seq) and long-read isoform sequencing (Iso-seq) transcriptomic data.

Included here are the primary assemblies (representing a non-redundant haploid genome) for each species (*.primary.fa), alternate loci (alternate representations of loci found in a largely haploid assembly; *.haplotypes.fa) and annotations (*.gff3). Metadata for each assembly can be found in the included spreadsheets (metadata.xlsx). 

This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see https://www.sanger.ac.uk/about/research-policies/open-access-science/.

This repository will be updated with a complete list of collaborators/authors prior to publication. Please contact Duncan Berger (db22@sanger.ac.uk) with questions regarding pre-publication use of this dataset.