Published July 19, 2022 | Version v1
Preprint Open

Recurring issues in meta-analysis on the reporting and interpretation of heterogeneity

Authors/Creators

  • 1. Oregon State University
  • 2. Pfizer
  • 3. University of Adelaide

Description

Meta-analysis is a fundamental tool for quantitatively pooling results from individual studies to inform evidenced-based decision for medicines. However, there is a recurring issue in many meta-analysis papers—including in prestigious journals—on the reporting and interpretation of the heterogeneity of effect sizes (ES), which can cause misleading interpretation of the main findings

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