A COMPARITIVE STUDY ON DIFFERENT METHODS USED FOR BUILDING 3-DIMENSIONAL MODELS OF PROTEIN

The concept of protein modelling or building of three-dimensional models of proteins using various methods is increasingly gaining sight of the researchers because of the various benefits derived from it that include not only identifying the type but also the function of the protein based on the model predicted. There are two types of methods, template-based methods and non-template-based methods used for modelling the protein structure using various logics. These include homology modelling, threading and ab-initio methods. The ab-initio method is template-independent unlike the other two methods which are templatebased. Here, all the three methods have been reviewed in detail and to the best of the knowledge so as to provide better insight into the type of method we must use as per our requirement.