Published June 9, 2022 | Version v1

Simulations of Sec61 with a substrate-selective inhibitor, conformation 1

Authors/Creators

  • 1. Institute of Biotechnology, University of Helsinki

Description

Simulations for an alternative conformation of KZR-8445 bound to Sec61. Data for the conformation used in Rehan et al., Nature Chemical Biology 19, pages 1054–1062 (2023) are available at https://zenodo.org/record/7303653

Files

Files (7.1 GB)

Name Size
md5:1e464cbdd4fa0e61a089e18dd6748a79
1.1 kB Download
md5:4486fcbed2b9a41872021738ce3a01a8
11.5 MB Download
md5:eb730b89ab0b4a709e9c7475aad80d3b
648 Bytes Download
md5:29c18902a26ec9a235d89697f1e3a661
7.3 MB Download
md5:944968d9e6b17fc5fe096f4b903faf30
6.6 MB Download
md5:a39d08371e93219b2034fd16c902a58e
20.8 MB Download
md5:ed373e1fb907ebca4600cec6ecfe317a
9.9 MB Download
md5:b9866a219bcaf0c4de34926f7b77cdec
1.1 GB Download
md5:cb957710db50f81ccc5333f4ddb2d9d0
7.3 MB Download
md5:6194523ebf5a7584721e31901087ade9
6.6 MB Download
md5:7ffa43c5835f9f4b92cc9d6e481492bf
20.8 MB Download
md5:4eed97c09d2092f4ea108408a566ddb9
9.9 MB Download
md5:26c18b6ca3626c38ab105c39600bd083
1.1 GB Download
md5:0a77ad201ba4b22b1e7c1f29b7767ef5
7.3 MB Download
md5:9c760541f9a151dc3c46fee0476603e7
6.6 MB Download
md5:a1a2fbf0af079890732ac9ce8382b32d
20.8 MB Download
md5:6b1c33cf28c7e2913d0cc41d846e8916
9.9 MB Download
md5:4f30d6090c032f171d11fc4c9ec891b7
1.1 GB Download
md5:564a44f888fa0c0edaf7969d1578d87b
7.3 MB Download
md5:c1cc217e16b39cd9057bf110e6bdec00
6.6 MB Download
md5:ccc5e108e334b1b0bcce6f9a51451427
20.8 MB Download
md5:e5991ef417c4307c501c83adb1d1e212
9.9 MB Download
md5:d85a3d4076771656676538272ec97910
1.1 GB Download
md5:59978c1f4f81f10c7e85ccb9f29682d2
7.3 MB Download
md5:1800956712fbfb0e9cab16dc34186481
6.6 MB Download
md5:608acffcf52371f4deac7533e5a73d6d
20.8 MB Download
md5:7b441298afd76a962ed41d343314b8fb
9.9 MB Download
md5:fc856139b2fd283e3897fce000c16a17
1.1 GB Download
md5:1bf2efcd7fea22c123e74204a712e927
7.2 MB Download
md5:012c4bd8eea8724d487feddde8fc98c6
6.6 MB Download
md5:ede033d19ea94ea59795f1397a30b253
20.8 MB Download
md5:3c6bd2cc67eddf328cba8a0b8234267f
10.7 MB Download
md5:910b752fc429811fa05d0cf4371deb6a
605 Bytes Download
md5:8b0ba61b3cd809f730abcbabab817ee8
9.9 MB Download
md5:cc63cd58aa5c784c032bdb15cdf108d1
1.1 GB Download
md5:7aa5fdd1592320cdd5ec1b69c47b117d
2.9 MB Download