Published June 7, 2022
| Version v1
Dataset
Open
MRI data for "Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the spreading, aggregation, and toxicity of α-synuclein in vivo"
Authors/Creators
- Lackie, Rachel E.1
- de Miranda, Aline S.1
- Lim, Mei Peng1
- Novikov, Vladislav1
- Madner, Nimrod2
- Karunatilleke, Nadun C.3
- Rutledge, Benjamin S .3
-
Tullo, Stephanie4
- Brickenden, Anne3
- Maitland, Matthew E.R.1
- Greenberg, David2
- Gallino, Daniel5
- Luo, Wen6
- Ataram, Anoosha1
- Shlafer, Irina6
- Del Cid Pellitero, Esther7
- Schild-Poulter, Caroline1
- Durcan, Thomas M.6
- Fon, Edward A.6
- Duennwald, Martin3
- Beraldo, Flavio H.1
- Chakravarty, M. Mallar5
- Bussey, Timothy J.1
- Saksida, Lisa M.1
- Soreq, Hermona2
- Choy, Wing-Yiu3
- Prado, Vania F.1
- Prado, Marco A.M.1
- 1. Robarts Research Institute
- 2. The Edmond and Lily Safra Center for Brain Sciences
- 3. The University of Western Ontario
- 4. McGill University
- 5. Douglas Research Institute
- 6. Early Drug Discovery Unit, Montreal Neurological Institute
- 7. Montreal Neurological Institute
Description
Repository for magnetic resonance imaging data from the project titled "Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the spreading, aggregation, and toxicity of α-synuclein in vivo"
Contains the pre-processed ex vivo T1-weighted images (Bruker 7T; 70 micron isotropic voxel resolution) for WT mice, M83 homozygous, and M83 homozygous mice with one copy of the TPR transgene. Full subject list can be viewed with the prado_MRI_M83dTPR_subjectlist_final.csv file.
Whole brain region segmentations are available for these mice. These labels were generated using the MAGeT-Brain segementation pipleine (https://github.com/CobraLab/MAGeTbrain) and using a modified/merged version of the Allen brain atlas. The full list of regions included can be found in the file named Allen_brain_mapping_final.csv.
See readme.txt file for more information
Files
Allen_brain_mapping_final.csv
Files
(731.6 MB)
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