Published July 21, 2022 | Version v1

Results for blind docking Tocriscreen 2.0 compounds against AlphaFold2 structural modules of human and parasite proteins

  • 1. University of Wisconsin-Madison

Description

Docking (GNINA 1.0) of 1280 Tocriscreen 2.0 compounds against >4000 AlphaFold structures from humans and the parasitic nematode Brugia malayi

Results are provided as Pickle objects or GZipped CSVs.

Tuned machine learning models (random forest and XGBoost) are also included for classifying actives/decoys.

Files

Files (25.1 GB)

Name Size
md5:bf63a9e36c776443d9664384933d63a3
13.4 GB Download
md5:a1f57a84bb73b2048e40b755dad14fb9
33.0 MB Download
md5:26922289efbd9a0287e635b3ce11c269
144.5 MB Download
md5:83b681dd641660bf03323d96ba78a30a
129.5 MB Download
md5:089fd28d11929397f0a03e4eee629ffb
557.3 MB Download
md5:09713aaf667b048f3451e600610385f7
10.8 GB Download