Published March 31, 1961 | Version v1

Synthesis of New Local Anaesthetics. Part VI

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Diethylaminoacetyl-2-amino-4-phenyl-, -4-p-chlorophenyl-, -4-p-bromophenyl-, -4-methyl- and piperidinoacetyl­-2-amino-4-p-bromophenyl-thiazoles have been synthesised and their local anaesthetic activities tested. The hydrochloride of diethyaminoacetyl-2-amino-4-p-chlorophenylthiazole has been found to be the most potent amongst the compounds described.

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