Published August 31, 1963
| Version v1
Journal article
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Approaches to Total Synthesis of Azasteroids. Part I. A Study of Methods for Introducing Nitrogen at Position 8 of Steroidal Nucleus
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Reaction of unsaturated lactone (VIII) with amines is shown to be a convenient method for introducing nitrogen into the ring system. Hydrogenation of (VIII) has been investigated and stereochemistry of the corresponding saturated lactones (IV and V) delineated.