A very rare malignant tumor of the thyroid gland: A case report of primary osteosarcoma

Osteosarcoma forms a small percentage of rare malignant non-epithelial neoplasms of the thyroid gland and has been reported in only a few dozen cases.

A 61-year-old female patient was hospitalized for operation due to enlarged tumor in the right thyroid lobe and substernal goiter seen in thyroid USG, and shortness of breath that continued for ten days and developed suddenly. Bilateral total thyroidectomy was performed to patient and in order to prevent tracheomalacia, trachea was fixed to the skin due to its deviation to the left and soft consistency. The pathology result was reported as primary thyroid osteosarcoma.

Differential diagnosis of a rapidly growing nodule in the thyroid gland includes primary or secondary tumor or cyst. If ultrasound and/or CT show compact, regular calcifications throughout the mass without mass findings, the primary extraosseous osteosarcoma of the thyroid gland should be included in the differential diagnosis. In the differential diagnosis of the nodule, which grows rapidly in the thyroid gland and causes sudden shortness of breath, the primary osteosarcoma tumor of the thyroid should be considered and rapid surgery should be performed