Reactions of Ninhydrin with N-Substituted Anilines and Substituted Guanidine

Department of chemistry, Dacca University, Bangladesh

Manuscript received 5 May 1973; revised 13 July 1973; accepted 24 July 1973

Ninhydrin (I) reacts with N-methyl-, N-ethyl- and N-benzyl- aniline to yield, 1,3-indandione derivatives of type II. These products are stable and yield well-crystallised acetyl derivatives. A similar reaction takes place between I and 1,3-diphenylguanidine to yield III. The reaction of I with diphenylarnine proceeds differently to give a compound of the structure IV.