Individual-donor scRNA-Seq datasets, as Seurat 4.0.5 objects

The provided datasets correspond to the analyses of individual donor single-cell RNA Sequencing (scRNA-Seq) datasets, before their integration. The datasets have been saved as Seurat v4.0.5 objects. For clustering, we used default settings in Seurat 4.0.5 (resolution 0.8) and increased resolution, if necessary, to separate epithelium in proximal and distal. 

The *_clusters.pdf files show the suggested clusters in the individual datasets and the  *_indiv_anno1.pdf files show the cell annotations according to the 84 cell states, described in the study with title "Developmental origins of cell heterogeneity in the human lung" (1st preprint version doi: https://doi.org/10.1101/2022.01.11.475631).

The "*_cluster_annotations.csv" files provide information about the suggested annotations of the clusters.

The "*_object_raw_and_log_counts.RData" objects contain the metadata and the UMI-counts [raw and log2(counts+1)] for each donor scRNA-Seq dataset.