Published May 17, 2021 | Version v1
Journal article Open

Candida albicans/Macrophage Biointerface on Human and Porcine Decellularized Adipose Matrices

  • 1. Departamento de Bioquímica y Biología Molecular, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain
  • 2. TECNALIA, Basque Research and Technology Alliance (BRTA), E20009 Donostia-San Sebastian, Spain

Description

Effects of human and porcine decellularized adipose matrices (DAMs), obtained by either enzymatic or organic solvent treatment, on the macrophage/Candida albicans interface. Differences on the activation of macrophages cultured on either human- or porcine-derived DAMs, evidencing changes in the macrophage actin cytoskeleton, such as distinct F-actin-rich membrane structures to surround the pathogen.

Notes

This work was supported by the European Horizon 2020 - FET OPEN Program under Grant No. 829060 ("NeuroStimSpinal"; URL: www.neurostimspinal.eu/")

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https://www.neurostimspinal.eu/ (URL)

Funding

NeuroStimSpinal – A STEP FORWARD TO SPINAL CORD INJURY REPAIR USING INNOVATIVE STIMULATED NANOENGINEERED SCAFFOLDS 829060
European Commission