Summary statistics from "Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers"
- 1. University of Leipzig
- 2. LIFE Research Center for Civilization Diseases
- 3. Department of Cardiology, Angiology and Intensive Care, Klinikum Lippe
- 4. Medical Campus Kiel, University Hospital Schleswig-Holstein
Description
The zipped csv-file is comma-delimited and contains the following columns:
identifier: Probe number and associated active substance
PROBE_ID.Adult: Probe number
logFC.Adult: log fold change of specific probe in LIFE-Adult
SE.Adult: Stand error for probe in LIFE-Adult
P.Value.Adult: p-value for probe in LIFE-Adult
qval.Adult: q-value for probe in LIFE-Adult
medi.Adult: associated active substance in in LIFE-Adult
P.Value.Heart: p-value for probe in LIFE-Heart
logFC.Heart: p-value for probe in LIFE-Heart
SE.Heart: Standard error for probe in LIFE-Heart
qval.Heart: q-value for probe in LIFE-Heart
medi.Heart: associated active substance in LIFE-Heart
symbol_INGENUITY: Gene associated with probe according to Ingenuity
description_INGENUITY: Description of gene associated with probe according to Ingenuity
For LIFE-Adult the results were calculated for all probes associated with the relevant 83 active substances described. For LIFE-Heart results were only calculated for probes that were also available LIFE-Adult.