HEMODYNAMIC CHANGES IN LOW DOSE INTRATHECAL DEXMEDETOMIDINE AND CLONIDINE AS ADJUVANT TO BUPIVACAINE - A COMPARATIVE STUDY
Authors/Creators
- 1. Senior Resident, Dept of Paediatrics, Tripura Medical College, Hapania, Tripura.
- 2. Assoc Professor, Dept of Anaesthesiology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra.
- 3. Professor and HOD, Dept of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra.
- 4. Junior Resident, Dept of Biochemistry, Agartala Government Medical College, Agartala, Tripura.
Description
Background : To evaluate the effect of low dose intrathecal dexmedetomidine and clonidine as adjuvant to bupivacaine on hemodynamic parameters of the patients . A total of 60 patients , scheduled for lower abdominal , lower limb and gynaecological procedures were selected to participate in this prospective , randomised double blind study . After injecting the drug time were noted (T0) and the patient were turned to supine position . Preoperative systolic and diastolic blood pressure , Heart rate were noted at specific time interval.
Results : Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure were compared in both the groups and there was no statistically significant difference between the two groups .
Conclusions : Both clonidine and dexmedetomidine as adjuvant to bupivacaine showed fall in heart rate , systolic blood pressure , diastolic blood pressure and mean arterial blood pressure . However there was no statistically significant difference between the two groups in these parameters.
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