Published March 1, 2022 | Version v1

The role and mechanism of TLR4-siRNA in the impairment of learning and memory in young mice induced by isofurane

  • 1. Department of Stomatology, Jiangxi Provincial People's Hospital
  • 2. Department of General Surgery, Jiangxi Provincial People's Hospital
  • 3. Department of Anesthesiology, Jiangxi Provincial People's Hospital

Description

This package contains six files:

Supplementary Table 1. Morris water maze test results of each group;

Supplementary Table 2. TLR4, TNF-ɑ and IL-6 expressions in the hippocampus of each group detected with qPCR and WB;

Supplementary Table 3. Serum TNF-ɑ and IL-6 levels of mice in each group detected with ELISA;

Supplementary Table 4. Apoptosis rate detected with TUNEL staining;

Supplementary Table 5. BDNF and CREB1 mRNA expressions detected with qPCR;

Supplementary Table 6. BDNF, CREB1, ERK1/2 and JNK protein expressions detected with WB.

Notes

This study was supported by the Natural Science Foundation of Jiangxi (Grant No. 20151BAB205103)

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