Model-based time trend adjustments in platform trials with non-concurrent controls

Presentation for the EU-PEARL webinar on the use of non-concurrent controls in platform trials (https://eu-pearl.eu/workshops/non-concurrent-controls-in-platform-trials/).

This work is based on the paper:

"On model-based time trend adjustments in platform trials with non-concurrent controls". (2021). M. Bofill Roig, P. Krotka, CF. Burman, E. Glimm, K. Hess, P. Jacko, F. Koenig, D. Magirr, P. Mesenbrink, K. Viele, and M. Posch. arXiv:2112.06574 [stat.ME]

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EU-PEARL (EU Patient-cEntric clinicAl tRial pLatforms) project has received funding from the Innovative Medicines Initiative (IMI) 2 Joint Undertaking (JU) under grant agreement No 853966. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA and Children’s Tumor Foundation, Global Alliance for TB Drug Development non-profit organisation, Springworks Therapeutics Inc.