Published February 4, 2022 | Version v1
Journal article Open

Brain simulation as a cloud service: The Virtual Brain on EBRAINS

Authors/Creators

  • 1. Berlin Institute of Health at Charité – Universitätsmedizin Berlin
  • 2. Codemart
  • 3. Forschungszentrum Jülich
  • 4. Swiss Federal Institute of Technology Lausanne
  • 5. Aix Marseille Université
  • 6. Forschungszentrum
  • 7. Ghent University
  • 8. Université Paris-Saclay
  • 9. University Medicine Greifswald
  • 10. De Montfort University
  • 11. University of Vienna
  • 12. Universitat Pompeu Fabra
  • 13. Baycrest Health Sciences
  • 14. University Medical Center Hamburg-Eppendorf
  • 15. CSCS Swiss National Supercomputing Centre
  • 16. University of Oslo
  • 17. Codebox

Description

The Virtual Brain (TVB) is now available as open-source services on the cloud research platform EBRAINS. It offers software for constructing, simulating and analysing brain network models including the TVB simulator; magnetic resonance imaging (MRI) processing pipelines to extract structural and functional brain networks; combined simulation of large-scale brain networks with small-scale spiking networks; automatic conversion of user-specified model equations into fast simulation code; simulation-ready brain models of patients and healthy volunteers; Bayesian parameter optimization in epilepsy patient models; data and software for mouse brain simulation; and extensive educational material. TVB cloud services facilitate reproducible online collaboration and discovery of data assets, models, and software embedded in scalable and secure workflows, a precondition for research on large cohort data sets, better generalizability, and clinical translation.

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Additional details

Funding

European Commission
ICEI - Interactive Computing E-Infrastructure for the Human Brain Project 800858
European Commission
VirtualBrainCloud - Personalized Recommendations for Neurodegenerative Disease 826421
European Commission
HBP SGA3 - Human Brain Project Specific Grant Agreement 3 945539
European Commission
HBP SGA2 - Human Brain Project Specific Grant Agreement 2 785907
European Commission
BrainModes - Personalized whole brain simulations: linking connectomics and dynamics in the human brain 683049