Synthesis of some Oxazolo-, lmidazolo-, Selenadiazolo-, Thiadiazolo-, Azetidinono- and Thiazolidinono-8- hydroxyquinolines

Chemistry Department, Faculty of Science, Assiut University, Assiut, Egypt

Manuscript received 20 March 1986, accepted 26 November 1986

Some new 5(7)-oxazolo- and/or imidazolo-8-hy droxyquin(,line (4a - f) were prepared through the reaction of 5(7) formyl-8 hydroxyquino ines (1, 2) with o-aminophenol, 1-amino 2-naphthol and o-phenylenediamine by fusion in presence of piperidine as a catalyst Also, 5-selenadiazolo-, thiadiazolo-, azttidinono- and thiazolidinono-8-hydroxy­guillotines (6, 7. 9a - c, 10a - c) were prepared by the reaction of 5-acetylsanicarbazone­8-hydrox3quinoline (4) and the Schiff bases (8a - c) with selenium dioxide, thionyl chloride, chioroacetyl chloride and thioglycolic acid, respectively.