Diurnal and circadian rhythmicity of the human blood transcriptome overlaps with organ and tissue specific expression of a non-human primate

Diurnal and circadian rhythmicity of the human blood transcriptome overlaps with organ and tissue specific expression of a non-human primate. Monitoring rhythmicity in tissues/organs holds promise for circadian medicine, however most tissues and organs are not easily accessible in humans and alternative approaches to quantify circadian rhythmicity are needed. We investigated the overlap between rhythmic transcripts in human blood and transcripts shown to be rhythmic in 64 tissues/organs of the baboon, how these rhythms are aligned with light-dark cycles and each other, and whether timing of tissue-specific rhythmicity can be predicted from a blood sample. R code used to generate the analyses can be found here.