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Published October 5, 2015 | Version v1
Dataset Open

Modeling exosome complexes from cross-link MS data

  • 1. Laboratory of Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, New York, New York, USA.
  • 2. Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, California, USA; Institut Pasteur, Paris, France.
  • 3. Laboratory of Cellular and Structural Biology, The Rockefeller University, New York, New York, USA.
  • 4. Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, USA; California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, California, USA.

Description

This repository contains the modeling scripts, the ensemble of models, and the results of the analysis for the modeling of the S.cerevisiae exosome complex (named exo10, comprising of Rrp40, Rrp4, Csl4, Rrp45, Rrp46, Rrp42, Rrp43, Mtr3, Ski6 and Rrp44), in presence of Ski7 (exo10+Ski7 below) or Rrp6 (exo10+Rrp6 below) proteins. The modeling is performed based on cross-link Mass-Spectrometry data, crystallographic structures, and comparative models.

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exosome-v1.0.zip

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