Published February 11, 2022
| Version v1
Dataset
Open
Summary Statistics from "Genetically regulated gene expression and proteins revealed discordant effects" (LWAS of biomarker)
Description
Summary statistics of 92 blood protein levels. The corresponding publication is currently under revision.
The zipped txt file is tab-delimited and contains the following columns:
- protein: protein name abbreviation
- cytoband: genomic region
- gene: gene name abbreviation
- setting: either "combined" (adj. for sex & age) or sex-stratified ("males", "females"; adj. for age)
- variant_id_hg19: SNP ID according to hg19
- variant_id_hg38: SNP ID according to hg19
- chr: chromosome
- pos_hg19: base position according to hg19
- pos_hg38: base position according to hg19
- effect_allele: also known as counted allele in additive model
- other_allele: not-counted allele
- eaf: effect allele frequency
- maf: minor allele frequency
- info: imputation info score
- n_samples: number of samples
- beta: effect estimate
- se: standard error
- zscore: Z-statistic
- pvalue: p-value
- FDR: FDR by gene and setting
- BBFDR: hierarchical FDR by setting
- hierFDR: TRUE if SNP is significant after hierarchical FDR
Files
Files
(36.5 MB)
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md5:6f8dbf529247a33751fa58ef100c9c70
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